SCHEMBL7549110

SCHEMBL7549110

CCCCCCCCCCCCCCC[CH]Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
THRB P10828 1/20 0.50
FAAH O00519 3/20 0.46
TRPV1 Q8NER1 1/20 0.46
DNM1 Q05193 3/20 0.45
ALDH1A1 P00352 1/20 0.45
EP300 Q09472 1/20 0.41
GMNN O75496 1/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX15 P16050 1/20 0.39
APEX1 P27695 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL614356 1.00
SCHEMBL4892754 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4464561 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL613389 1.00
SCHEMBL2008106 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4887747 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL10430519 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL8752644 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL10430512 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL4892354 1.00 TSHR (0.52) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0598751-B1 SYNTHESIS OF IOVERSOL USING CHLOROACETYL CHLORIDE MALLINCKRODT MEDICAL INC (US) 1999-03-24 EP claimed
CN-115975205-B Preparation method of self-emulsifying amino silicone oil and amino silicone oil emulsion 厦门弘嘉顺逸科技有限公司 2023-11-17 CN disclosed
CN-116918965-A Food composition capable of correcting vision and application thereof 河北省葆睛生物科技有限公司 2023-10-24 CN disclosed
CN-115975205-A Preparation method of self-emulsifying amino silicone oil and amino silicone oil emulsion 厦门弘嘉顺逸科技有限公司 2023-04-18 CN disclosed
CN-111138312-B Schiff base Cu (II) complex with binaphthyl diamine as framework and preparation method thereof 中国科学院大连化学物理研究所 2021-11-09 CN disclosed
CN-111138312-A Schiff base Cu (II) complex with binaphthyl diamine as framework and preparation method thereof 中国科学院大连化学物理研究所 2020-05-12 CN disclosed
CN-1980990-B Nanocomposite and method for producing the same BRIDGESTONE CORP 2011-03-02 CN disclosed
US-20020173489-A1 COMPOSITIONS CONTAINING A MIXTURE OF PHOSPHOROUS COMPOUNDS AND ALKYLGLYCEROLS MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTER E.V. (DE) 2002-11-21 US disclosed
EP-0704425-B1 ADDITIVE COMPOSITION FOR LUBRICANT OR FUEL, LUBRICANT OR FUEL COMPOSITION CONTAINING THE SAME, AND NOVEL SUBSTITUTED HYDROXY AROMATIC ESTER DERIVATIVE IDEMITSU KOSAN CO (JP) 2002-09-04 EP disclosed
US-5916884-A CYTOTOXIC THERAPEUTIC COMPOUND; ANTITUMOR AGENT MAX-PLANCK-GESELLSCHAFT ZUR FOEDERUNG DER WISSENSCHAFTEN (DE) 1999-06-29 US disclosed
EP-0248858-B1 NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1990-02-28 EP disclosed
CN-87106919-A CROSS-LINKED ESTERS OF HYALURONIC ACID 1988-08-24 CN disclosed
EP-0248858-A1 NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE. MAX PLANCK GESELLSCHAFT (DE) 1987-12-16 EP disclosed
WO-1987003596-A2 NOVEL PHOSPHO-COMPOUNDS AND MEDICAMENTS CONTAINING THESE MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSC (DE) 1987-06-18 WO disclosed
EP-0225608-A2 Medicine Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1987-06-16 EP disclosed
EP-0224925-A2 Phosphorous compounds and medicines containing them Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1987-06-10 EP disclosed
US-4631272-A N-acylated 1-alkylamino-1-deoxy-ketose derivatives, a process for their preparation and their use BAYER AKTIENGESELLSCHAFT (DE) 1986-12-23 US disclosed
EP-0152856-A2 N-acylated 1-alkylamimo-1-desoxy ketose derivatives, method for their preparation and use BAYER AG (DE) 1985-08-28 EP disclosed
US-RE30279-E FROM ALKYL OR ARYL HALIDE WITH HALO-SUBSTITUTED TRIVALENT PHOSPHORUS COMPOUNDS AND PHOSPHORUS PENTASULFIDE OR -OXIDE STAUFFER CHEMICAL COMPANY (US) 1980-05-20 US disclosed
US-4178253-A 1,2,4-TRIAZOLE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1979-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173489-A1 COMPOSITIONS CONTAINING A MIXTURE OF PHOSPHOROUS COMPOUNDS AND ALKYLGLYCEROLS PHOSPHO1, PLCG2, PPIP5K2 TSHR 4720/4885THRB 4839/4885FAAH 455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.