Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 18/20 | 0.40 |
| ▸ | GABRD | O14764 | 18/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 18/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 18/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 18/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 18/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 18/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 18/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 18/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 18/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 18/20 | 0.40 |
| ▸ | GABRE | P78334 | 18/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 18/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 18/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 18/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 18/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549474 | 1.00 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7024789 | 0.84 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7024787 | 0.84 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7030914 | 0.75 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7030916 | 0.75 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7023816 | 0.68 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7023810 | 0.68 | GABRP (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7025972 | 0.67 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7025970 | 0.67 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9213379 | 0.65 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | RHONE-POULENC INC. | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045758-A1 | Pesticidal 1-arylpyrazoles | CYP1B1, CYP2E1, CYP1A1 | GABRP 1208/4885GABRD 2403/4885GABRA1 1171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.