Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.46 |
| ▸ | NPY1R | P25929 | 6/20 | 0.46 |
| ▸ | NPY2R | P49146 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8416482 | 0.92 | HDAC1 (0.47) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL537084 | 0.92 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RMCHR1 | |
| SCHEMBL8512961 | 0.91 | MCHR1 (0.42) | NPY4RNPY1RNPY2RNPY5RMCHR1 | |
| Hydrochloric Acid SCHEMBL7850288 | 0.91 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RMCHR1 | |
| Bromide SCHEMBL11101365 | 0.91 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8515668 | 0.89 | HDAC1 (0.45) | NPY4RNPY1RNPY2RNPY5RMCHR1 | |
| SCHEMBL8882210 | 0.86 | ITGB3 (0.44) | NPY4RNPY1RNPY2RNPY5RMCHR1 | |
| SCHEMBL27352129 | 0.84 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL8341764 | 0.84 | NPY4R (0.47) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL10434863 | 0.83 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11726094-B2 | Methods for determining DPP3 and therapeutic methods | 4TEEN4 Pharmaceuticals GmbH (DE) | 2023-08-15 | — | — | US | disclosed |
| EP-3896450-A1 | METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS | 4TEEN4 Pharmaceuticals GmbH (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3854817-A1 | METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS | 4TEEN4 Pharmaceuticals GmbH (DE) | 2021-07-28 | — | — | EP | disclosed |
| US-20200378977-A1 | METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS | 4TEEN4 Pharmaceuticals GmbH (DE) | 2020-12-03 | — | — | US | disclosed |
| US-20190145981-A1 | METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS | SPHINGOTEC THERAPEUTICS GMBH (DE) | 2019-05-16 | — | — | US | disclosed |
| EP-0659886-B1 | Enzymatic conversion of proteins using immobilized dictyostelium dipeptidylaminopeptidase | LILLY CO ELI (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-0595476-B1 | Dictyostelium dipeptidylaminopeptidase | LILLY CO ELI (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-1094118-A1 | Enzymatic conversion of precursor proteins using a dictyostelium dipeptidylaminopeptidase | ELI LILLY AND COMPANY (US) | 2001-04-25 | — | — | EP | disclosed |
| US-6027911-A | REMOVING AMINO-TERMINAL DIPEPTIDES FROM PRECURSOR POLYPEPTIDE BY IMMOBILIZING CATHEPSIN C ONTO SUPPORT SURFACE, THEN INCUBATING WITH POLYPEPTIDE AND RECOVERING PROCESSED POLYPEPTIDE | ELI LILLY AND COMPANY (US) | 2000-02-22 | — | — | US | disclosed |
| US-6008041-A | NUCLEOTIDE SEQUENCE WHICH ENCODES SINGLE POLYPEPTIDE WHICH CAN BE PROCESSED INTO MATURE PROTEIN; FOR GENETICALLY ENGINEERED PRODUCTION OF ENZYME | ELI LILLY AND COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0898615-A1 | BOVINE DIPEPTIDYLAMINOPEPTIDASE 1 | ELI LILLY AND COMPANY (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997042306-A1 | BOVINE DIPEPTIDYLAMINOPEPTIDASE 1 | ELI LILLY AND COMPANY (US) | 1997-11-13 | — | — | WO | disclosed |
| US-5565330-A | Method for removing N-terminal dipeptides from precursor polypeptides with dipeptidylaminopeptidase from Dictyostelium discoideum | ELI LILLY AND COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| US-5565349-A | ISOLATED FROM SLIME MOLDS; USEFUL IN REMOVING DIPEPTIDES FROM N-TERMINUS OF GENETICALLY ENGINEERED PEPTIDES | ELI LILLY AND COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0659886-A1 | Enzymatic conversion of proteins using immobilized dictyostelium dipeptidylaminopeptidase | ELI LILLY AND COMPANY (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0595476-A2 | Dictyostelium dipeptidylaminopeptidase | ELI LILLY AND COMPANY (US) | 1994-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190145981-A1 | METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS | DPP3, DPP4, DPP7 | NPY4R 852/4885NPY1R 1684/4885NPY2R 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.