Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 18/20 | 0.53 |
| ▸ | THRA | P10827 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545423 | 0.95 | NR3C1 (0.58) | NR3C1THRBTHRA | |
| SCHEMBL7249278 | 0.91 | NR3C1 (0.62) | NR3C1THRBTHRA | |
| SCHEMBL7547871 | 0.89 | NR3C1 (0.54) | NR3C1THRBTHRA | |
| SCHEMBL7547173 | 0.89 | NR3C1 (0.54) | NR3C1THRBTHRA | |
| SCHEMBL7548926 | 0.88 | NR3C1 (0.65) | NR3C1THRBTHRA | |
| SCHEMBL7553529 | 0.88 | NR3C1 (0.53) | NR3C1THRBTHRA | |
| SCHEMBL7552803 | 0.88 | NR3C1 (0.53) | NR3C1THRBTHRA | |
| SCHEMBL7546002 | 0.88 | NR3C1 (0.53) | NR3C1THRBTHRA | |
| SCHEMBL7549495 | 0.88 | NR3C1 (0.53) | NR3C1THRBTHRA | |
| SCHEMBL7594693 | 0.87 | NR3C1 (0.53) | NR3C1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002044120-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR III | KARO BIO AB (SE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002044120-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR III | KARO BIO AB (SE) | 2002-06-06 | — | — | WO | disclosed |