Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554509 | 0.92 | CCR2 (0.56) | CCR2AURKANPY5RALDH1A1KDM4E | |
| SCHEMBL7553600 | 0.89 | CCR2 (0.68) | CCR2AURKANPY5RALDH1A1KDM4E | |
| SCHEMBL7549699 | 0.88 | CCR2 (0.60) | CCR2ALDH1A1KDM4EHPGDACHE | |
| SCHEMBL7554047 | 0.85 | CCR2 (0.43) | CCR2AURKANPY5RALDH1A1KDM4E | |
| SCHEMBL7547688 | 0.84 | CCR2 (0.64) | CCR2ALDH1A1KDM4EHPGDACHE | |
| SCHEMBL7554497 | 0.84 | CCR2 (0.54) | CCR2AURKAACHEHRH3CYP1A2 | |
| SCHEMBL7159244 | 0.83 | CCR2 (0.51) | CCR2AURKANPY5RACHEHRH3 | |
| SCHEMBL7548839 | 0.83 | CCR2 (0.81) | CCR2ALDH1A1KDM4EHPGDACHE | |
| SCHEMBL7160102 | 0.82 | CCR2 (0.52) | CCR2ACHEHRH3CYP1A2CYP2D6 | |
| SCHEMBL7553586 | 0.82 | CCR2 (0.64) | CCR2ALDH1A1KDM4EHPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | WARNER-LAMBERT COMPANY (US) | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099054-A1 | 2-phenyl benzimidazole derivatives as MCP-1 antagonists | CCR1, CCR2, CCR8 | CCR2 2/4885AURKA 4675/4885NPY5R 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.