Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738454 | 0.83 | RARB (0.52) | ACACBRARARARBRARGCYP26A1 | |
| SCHEMBL7980207 | 0.82 | CYP26A1 (0.38) | ACACBRARARARBRARGCYP26A1 | |
| SCHEMBL6425787 | 0.81 | AKR1C3 (0.41) | ACACBRARARARBRARGCYP26A1 | |
| SCHEMBL5735781 | 0.81 | FFAR1 (0.44) | ACACBRARARARBRARGCYP26A1 | |
| SCHEMBL7980771 | 0.81 | RARB (0.38) | ACACBRARARARBRARGCYP26A1 | |
| SCHEMBL5737644 | 0.81 | — | — | |
| SCHEMBL5737179 | 0.81 | RARA (0.42) | ACACBRARARARBRARGCYP26A1 | |
| SCHEMBL5737929 | 0.77 | — | — | |
| SCHEMBL7684995 | 0.76 | SRC (0.35) | RARARARBRARGCYP26A1CYP3A4 | |
| SCHEMBL7982072 | 0.74 | RARB (0.36) | ACACBRARARARBRARGCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193578-A1 | Compounds having activity as inhibitors of cytochrome P450RAI | ALLERGAN, INC. | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193578-A1 | Compounds having activity as inhibitors of cytochrome P450RAI | RARA, RARB, RARG | ACACB 1070/4885RARA 1/4885RARB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.