⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359448 | 0.74 | — | — | |
| SCHEMBL8630779 | 0.70 | — | — | |
| SCHEMBL11814746 | 0.70 | — | — | |
| SCHEMBL4782922 | 0.67 | — | — | |
| SCHEMBL2359396 | 0.67 | — | — | |
| SCHEMBL23264159 | 0.62 | — | — | |
| SCHEMBL4799622 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL4786213 | 0.60 | GAA (0.34) | — | |
| SCHEMBL24377355 | 0.60 | — | — | |
| SCHEMBL676815 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11027242-B2 | Nanofiltration membranes and methods of use | NOVOMER, INC. (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3180329-B1 | TRIAZOLES AS NR2B RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| US-20190255488-A1 | NANOFILTRATION MEMBRANES AND METHODS OF USE | NOVOMER, INC. (US) | 2019-08-22 | — | — | US | disclosed |
| US-10323021-B2 | Triazoles as NR2B receptor inhibitors | Janssen Pharmaceuticals, Inc. (US) | 2019-06-18 | — | — | US | disclosed |
| US-20180282305-A1 | TRIAZOLES AS NR2B RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICALS INC (US) | 2018-10-04 | — | — | US | disclosed |
| US-20160288057-A1 | NANOFILTRATION MEMBRANES AND METHODS OF USE | NOVOMER, INC. (US) | 2016-10-06 | — | — | US | disclosed |
| EP-1242423-A1 | SUBSTITUTED 1,2,3-TRIAZOLO 1,5-a]QUINAZOLINES FOR ENHANCING COGNITION | MERCK SHARP & DOHME LTD. (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044250-A1 | SUBSTITUTED 1,2,3-TRIAZOLO[1,5-a]QUINAZOLINES FOR ENHANCING COGNITION | MERCK SHARP & DOHME LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |