⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16014586 | 0.74 | — | — | |
| SCHEMBL10644282 | 0.72 | — | — | |
| SCHEMBL10790381 | 0.70 | — | — | |
| SCHEMBL5431609 | 0.70 | — | — | |
| SCHEMBL10620564 | 0.67 | — | — | |
| SCHEMBL4351046 | 0.67 | — | — | |
| SCHEMBL23761187 | 0.67 | — | — | |
| SCHEMBL12341466 | 0.67 | L3MBTL1 (0.32) | — | |
| SCHEMBL17198716 | 0.67 | — | — | |
| SCHEMBL5924399 | 0.66 | NR1H2 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12384773-B2 | Thiazole compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| WO-2025096979-A1 | THIAZOLE COMPOUNDS AS KIT INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| US-20250145606-A1 | THIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-05-08 | — | — | US | disclosed |
| US-20250122172-A1 | SUBSTITUTED PYRIDINE AND PYRAZINE COMPOUNDS AS PDE4 INHIBITORS | DART NEUROSCIENCE LLC | 2025-04-17 | — | — | US | disclosed |
| WO-2025022310-A1 | A METHOD FOR PREPARING 1-ALKYL-1H-1,2,4-TRAIZOL-3-AMINE COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2025-01-30 | — | — | WO | disclosed |
| WO-2023205173-A1 | SUBSTITUTED PIPERIDINES AND SUBSTITUTED TETRAHYDROPYRIDINES AS IMMUNE-MODULATING COMPOUNDS | BLACKSMITH MEDICINES, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| US-20230075774-A1 | SUBSTITUTED PYRIDINE AND PYRAZINE COMPOUNDS AS PDE4 INHIBITORS | DART NEUROSCIENCE LLC (US) | 2023-03-09 | — | — | US | disclosed |
| WO-2022086920-A1 | GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE (QPCTL) PROTEIN INHIBITORS AND USES THEREOF | BLACKSMITH MEDICINES, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| US-11279691-B2 | Substituted pyridine and pyrazine compounds as PDE4 inhibitors | DART NEUROSCIENCE LLC (US) | 2022-03-22 | — | — | US | disclosed |
| US-11147275-B2 | Substituted trifluoromethyloxadiazoles for combating phytopathogenic fungi | BASF SE (DE) | 2021-10-19 | — | — | US | disclosed |
| US-5318982-A | Inhibiting crosslinking of proteins | THE ROCKEFELLER UNIVERSITY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0073562-B1 | HERBICIDAL TRIAZOLE UREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| EP-0103537-B1 | N-ARYLSULFONYL-N'-TRIAZOLYL UREA | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |
| US-4656273-A | Process for producing sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0132230-A2 | Process for the preparation of sulfonyl urea | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |
| EP-0103537-A2 | N-arylsulfonyl-N'-triazolyl urea | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |
| US-4421550-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0073562-A2 | Herbicidal triazole ureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-03-09 | — | — | EP | disclosed |
| US-4113717-A | Quaternized azo dyestuffs | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-12 | — | — | US | disclosed |