Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7550182

NCCCCC(N)C(=O)OCc1ccccc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.51

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.51
MMP2 P08253 1/20 0.50
ITGB3 P05106 4/20 0.45
ITGA2B P08514 4/20 0.45
DPP8 Q6V1X1 2/20 0.42
DPP7 Q9UHL4 2/20 0.42
ANPEP P15144 1/20 0.42
EPOR P19235 1/20 0.42
DPP9 Q86TI2 1/20 0.42
ECE1 P42892 1/20 0.41
SLC15A1 P46059 1/20 0.41
LAP3 P28838 1/20 0.41
GSR P00390 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7550184 1.00 LTA4H (0.51) LTA4HMMP2ITGB3ITGA2BDPP8
SCHEMBL676143 0.92 LTA4H (0.57) LTA4HMMP2DPP8DPP7ANPEP
SCHEMBL730307 0.92 LTA4H (0.57) LTA4HMMP2DPP8DPP7ANPEP
Hydrochloric Acid SCHEMBL9394094 0.90 LTA4H (0.56) LTA4HMMP2ITGB3ITGA2BDPP8
SCHEMBL8618743 0.90 LTA4H (0.56) LTA4HMMP2ITGB3ITGA2BDPP8
Hydrochloric Acid SCHEMBL29401201 0.90 LTA4H (0.56) LTA4HMMP2ITGB3ITGA2BDPP8
Hydrochloric Acid SCHEMBL9394090 0.90 LTA4H (0.56) LTA4HMMP2ITGB3ITGA2BDPP8
Hydrochloric Acid SCHEMBL6671170 0.89 LTA4H (0.55) LTA4HMMP2ITGB3ITGA2BDPP8
Ethylene Glycol SCHEMBL28081329 0.88 LTA4H (0.54) LTA4HMMP2ITGB3ITGA2BDPP8
SCHEMBL4622400 0.87 LTA4H (0.52) LTA4HMMP2DPP8DPP7ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941123-B1 NUCLEIC ACID COMPLEXED WITH CATIONIC POLYMER USEFUL FOR GENE THERAPY HYBRID SYSTEMS LTD (GB) 2002-06-12 EP disclosed
US-6312727-B1 SYNTHETIC POLYMER CARRIER VEHICLE FOR DELIVERY OF NUCLEIC ACID TO TARGET CELLS IN BIOLOGICAL SYSTEMS HYBRID SYSTEMS LIMITED (GB) 2001-11-06 US disclosed
EP-0941123-A2 DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS SCHACHT, Etienne Honoré (BE) 1999-09-15 EP disclosed
WO-1998019710-A2 DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS SCHACHT ETIENNE HONORE (BE) 1998-05-14 WO disclosed