SCHEMBL7550258

SCHEMBL7550258

CCCCCCCCCCC(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.60
CTSS P25774 3/20 0.60
NOD1 Q9Y239 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7550254 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL7839929 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL2706071 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL1926493 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL7555645 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL7555646 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL6818249 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL7547359 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL5050858 1.00 CTSK (0.60) CTSKCTSSNOD1
SCHEMBL17356699 1.00 CTSK (0.60) CTSKCTSSNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4093730-A1 HDAC DEGRADER University of Leicester (GB) 2022-11-30 EP disclosed
US-20170342106-A1 METHOD OF MAKING PRODRUGS AND TARGETED THERAPEUTIC COMPOUNDS INSPYR THERAPEUTICS, INC. (US) 2017-11-30 US disclosed
EP-3221702-A1 METHOD OF MAKING PRODRUGS AND TARGETED THERAPEUTIC COMPOUNDS Inspyr Therapeutics, Inc. (US) 2017-09-27 EP disclosed
WO-2016081229-A1 METHOD OF MAKING PRODRUGS AND TARGETED THERAPEUTIC COMPOUNDS GENSPERA, INC. (US) 2016-05-26 WO disclosed
WO-2002053572-A1 DELIVERY SYSTEMS ALCHEMIA PTY LTD (AU) 2002-07-11 WO disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 US disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170342106-A1 METHOD OF MAKING PRODRUGS AND TARGETED THERAPEUTIC COMPOUNDS CYP21A2, FURIN, CYP26B1 CTSK 631/4885CTSS 791/4885NOD1 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.