Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7555123 | 0.78 | CFTR (0.44) | CFTRGRM2 | |
| SCHEMBL1499434 | 0.76 | CFTR (0.45) | CFTRGRM2POLBFASNCTSK | |
| SCHEMBL4624725 | 0.76 | CFTR (0.45) | CFTRGRM2POLBFASNCTSK | |
| SCHEMBL379440 | 0.76 | CFTR (0.45) | CFTRGRM2POLBFASNCTSK | |
| SCHEMBL27260115 | 0.76 | CFTR (0.45) | CFTRGRM2POLBFASNCTSK | |
| SCHEMBL11427124 | 0.76 | TSHR (0.53) | CFTRGRM2 | |
| SCHEMBL7549855 | 0.73 | TSHR (0.42) | POLB | |
| SCHEMBL7550250 | 0.71 | TSHR (0.41) | POLB | |
| SCHEMBL50937 | 0.69 | TSHR (0.39) | CFTRGRM2 | |
| SCHEMBL9790871 | 0.67 | TSHR (0.44) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002051883-A1 | SYNTHESIS OF NOVEL HETEROCYCLIC MOLECULES OXYGENATED BY METATHESIS REACTION ON SOLID SUPPORT USING NOVEL SILYLATED LINKERS | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | claimed |
| WO-2002051883-A1 | SYNTHESIS OF NOVEL HETEROCYCLIC MOLECULES OXYGENATED BY METATHESIS REACTION ON SOLID SUPPORT USING NOVEL SILYLATED LINKERS | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | disclosed |