SCHEMBL7550602

SCHEMBL7550602

Oc1c(Cl)ccc(F)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.40
TSHR P16473 7/20 0.40
CYP3A4 P08684 4/20 0.40
HPGD P15428 4/20 0.40
MAPK1 P28482 2/20 0.40
DPP4 P27487 1/20 0.39
ALDH1A1 P00352 4/20 0.39
TDP1 Q9NUW8 1/20 0.39
CASP1 P29466 1/20 0.38
RECQL P46063 1/20 0.38
DAO P14920 1/20 0.36
TNF P01375 1/20 0.35
RIPK1 Q13546 1/20 0.35
SLC2A1 P11166 1/20 0.34
CA3 P07451 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL66253 0.83 ERN1 (0.39) HSD17B10TSHRCYP3A4HPGDMAPK1
SCHEMBL31506484 0.77 CYP3A4 (0.55) HSD17B10TSHRCYP3A4HPGDMAPK1
SCHEMBL581831 0.77 CYP3A4 (0.55) HSD17B10TSHRCYP3A4HPGDMAPK1
SCHEMBL14113092 0.75 DPP4 (0.37) HSD17B10TSHRCYP3A4MAPK1DPP4
SCHEMBL18893999 0.75 DAO (0.34) HPGDALDH1A1TDP1RECQLDAO
SCHEMBL24069857 0.75 ALDH1A1 (0.41) HSD17B10TSHRCYP3A4MAPK1DPP4
SCHEMBL18894025 0.75 DPP4 (0.37) HSD17B10TSHRCYP3A4MAPK1DPP4
SCHEMBL12886366 0.75 ALDH1A1 (0.40) CYP3A4ALDH1A1DAOTNFRIPK1
SCHEMBL101941 0.75 CA1 (0.38) HSD17B10TSHRCYP3A4HPGDMAPK1
SCHEMBL28056186 0.75 ALDH1A1 (0.38) HSD17B10TSHRCYP3A4HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872476-B1 Herbicidal substance based on 2,6-dichloro-3-fluoro-benzonitrile and new intermediate compounds BAYER AG (DE) 2002-07-03 EP claimed
WO-2016059242-A2 TRACERS INSTITUTT FOR ENERGITEKNIKK (NO) 2016-04-21 WO disclosed
US-4060562-A SULFUR CONTAINING CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed