Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 14/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098134 | 0.89 | ERBB2 (0.57) | EGFRERBB2 | |
| SCHEMBL4352969 | 0.81 | EGFR (0.84) | EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL6768052 | 0.81 | EGFR (0.83) | EGFRERBB2 | |
| SCHEMBL7551367 | 0.81 | ERBB2 (0.58) | EGFRERBB2 | |
| SCHEMBL2099818 | 0.74 | EGFR (0.77) | EGFRERBB2 | |
| SCHEMBL2099497 | 0.73 | EGFR (1.00) | EGFRERBB2 | |
| SCHEMBL2099689 | 0.73 | EGFR (0.78) | EGFRERBB2 | |
| SCHEMBL7005290 | 0.73 | ERBB2 (0.85) | EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL3326222 | 0.73 | EGFR (0.98) | EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL30957044 | 0.73 | EGFR (0.98) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912559-B1 | FUSED HETEROCYCLIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS | GLAXO GROUP LTD (GB) | 2002-11-06 | — | — | EP | claimed |