Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180689 | 0.87 | L3MBTL1 (0.61) | L3MBTL1NAMPTGAAHDAC1CA1 | |
| SCHEMBL28619767 | 0.87 | HDAC1 (0.50) | L3MBTL1NAMPTGAAHDAC1NPC1 | |
| SCHEMBL27420133 | 0.87 | GAA (0.51) | L3MBTL1NAMPTGAAHDAC1NPC1 | |
| SCHEMBL8139001 | 0.85 | L3MBTL1 (0.49) | L3MBTL1NAMPTGAAHDAC1NPC1 | |
| SCHEMBL11687632 | 0.85 | NPC1 (0.56) | NAMPTGAANPC1RAB9ACA1 | |
| SCHEMBL11957489 | 0.84 | L3MBTL1 (0.53) | L3MBTL1NAMPTGAAHDAC1NPC1 | |
| SCHEMBL7652554 | 0.84 | NPC1 (0.58) | L3MBTL1NAMPTGAAHDAC1NPC1 | |
| SCHEMBL16192946 | 0.84 | NPC1 (0.58) | L3MBTL1NAMPTGAAHDAC1NPC1 | |
| SCHEMBL17637647 | 0.84 | L3MBTL1 (0.48) | L3MBTL1NAMPTGAAHDAC1NPC1 | |
| SCHEMBL16192926 | 0.84 | L3MBTL1 (0.48) | L3MBTL1NAMPTGAAHDAC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027096-A1 | AMINOMETHYL-(HETERO)ARYL DERIVATIVES AND THEIR USE AS TRYPTASE INHIBITORS | TULARIK LIMITED (GB) | 2001-04-19 | — | — | WO | disclosed |