Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.47 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.33 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505912 | 1.00 | P2RY12 (0.47) | P2RY12NAE1UBA3 | |
| SCHEMBL7509281 | 0.89 | P2RY12 (0.53) | P2RY12NAE1UBA3 | |
| SCHEMBL7509278 | 0.89 | P2RY12 (0.53) | P2RY12NAE1UBA3 | |
| SCHEMBL7506183 | 0.88 | P2RY12 (0.48) | P2RY12NAE1UBA3 | |
| SCHEMBL7509705 | 0.84 | P2RY12 (0.57) | P2RY12 | |
| Bicarbonate SCHEMBL7514070 | 0.81 | P2RY12 (0.52) | P2RY12NAE1UBA3 | |
| SCHEMBL7507169 | 0.81 | P2RY12 (0.72) | P2RY12 | |
| SCHEMBL7509882 | 0.81 | P2RY12 (0.70) | P2RY12 | |
| SCHEMBL7507158 | 0.81 | P2RY12 (0.72) | P2RY12 | |
| SCHEMBL7509891 | 0.81 | P2RY12 (0.70) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998475-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-04-17 | — | — | EP | disclosed |
| US-6166022-A | Compounds | ASTRAZENECA UK LIMITED (GB) | 2000-12-26 | — | — | US | disclosed |