Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7551968

N.Nc1ccc(Nc2ccc(N)cc2S(=O)(=O)O)cc1

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.97
ALDH1A1 P00352 4/20 0.80
MAPT P10636 4/20 0.80
GAA P10253 3/20 0.80
TDP1 Q9NUW8 3/20 0.80
KDM4E B2RXH2 3/20 0.80
POLB P06746 2/20 0.80
RECQL P46063 2/20 0.80
CASP6 P55212 2/20 0.80
L3MBTL1 Q9Y468 2/20 0.80
MEN1 O00255 2/20 0.80
KMT2A Q03164 2/20 0.80
ELAVL1 Q15717 1/20 0.80
APEX1 P27695 2/20 0.79
NSD2 O96028 1/20 0.79
APOBEC3A P31941 1/20 0.79
APOBEC3G Q9HC16 1/20 0.79
NT5E P21589 2/20 0.72
GNG2 P59768 4/20 0.53
GNB1 P62873 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29516556 0.98 RAPGEF4 (1.00) RAPGEF4ALDH1A1MAPTGAATDP1
SCHEMBL866958 0.98 RAPGEF4 (1.00) RAPGEF4ALDH1A1MAPTGAATDP1
Hydrochloric Acid SCHEMBL8652689 0.97 RAPGEF4 (0.97) RAPGEF4ALDH1A1MAPTGAATDP1
SCHEMBL9189649 0.97 RAPGEF4 (0.97) RAPGEF4ALDH1A1MAPTGAATDP1
Trimethylammonium SCHEMBL7555318 0.92 RAPGEF4 (0.88) RAPGEF4ALDH1A1MAPTGAATDP1
SCHEMBL10705815 0.90 RAPGEF4 (0.85) RAPGEF4ALDH1A1MAPTGAATDP1
SCHEMBL10878674 0.89 RAPGEF4 (0.82) RAPGEF4ALDH1A1MAPTGAATDP1
SCHEMBL7814270 0.89 GAA (1.00) RAPGEF4ALDH1A1MAPTGAATDP1
SCHEMBL343582 0.89 GAA (1.00) RAPGEF4ALDH1A1MAPTGAATDP1
SCHEMBL30040076 0.89 GAA (1.00) RAPGEF4ALDH1A1MAPTGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747418-B1 Aromatic polyimide and gas separation UBE INDUSTRIES (JP) 2002-07-03 EP disclosed
US-5744575-A Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1998-04-28 US disclosed
EP-0747418-A1 Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1996-12-11 EP disclosed