Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19146819 | 0.91 | ANPEP (0.56) | ANPEPALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL3112742 | 0.91 | ANPEP (0.56) | ANPEPALDH1A1KMT2AMAPTMEN1 | |
| Ammonia Solution, Strong SCHEMBL20237223 | 0.89 | ANPEP (0.54) | ANPEPALDH1A1KMT2AMAPTMEN1 | |
| Carbamic Acid SCHEMBL15635796 | 0.81 | HDAC8 (0.60) | ANPEPKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL20515139 | 0.81 | ALDH1A1 (0.47) | ANPEPALDH1A1CYP1A2CYP2D6SLC6A2 | |
| SCHEMBL1749634 | 0.81 | ALDH1A1 (0.68) | ANPEPALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL8843501 | 0.80 | ANPEP (0.50) | ANPEPALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL23415475 | 0.79 | ANPEP (0.60) | ANPEPKMT2AMEN1CYP2D6BCHE | |
| SCHEMBL7068007 | 0.79 | ANPEP (0.60) | ANPEPKMT2AMEN1CYP2D6BCHE | |
| SCHEMBL13484773 | 0.79 | KMT2A (0.53) | ANPEPALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |