SCHEMBL755274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL755275	1.00	NR1H4 (0.49)	NR1H4ALDH1A1ALKBH1MEN1KMT2A
	SCHEMBL754203	0.90	MAPT (0.42)	NR1H4ALDH1A1MEN1KMT2AL3MBTL1
	SCHEMBL754204	0.90	MAPT (0.42)	NR1H4ALDH1A1MEN1KMT2AL3MBTL1
	SCHEMBL13754872	0.82	NR1H4 (0.50)	NR1H4ALDH1A1MEN1KMT2APRMT5
	SCHEMBL16921585	0.77	GRM4 (0.39)	NR1H4ALDH1A1MEN1KMT2APRMT5
	SCHEMBL13754870	0.77	NR1H4 (0.47)	NR1H4ALDH1A1MEN1KMT2APRMT5
	SCHEMBL755251	0.76	NR1H4 (0.49)	NR1H4ALDH1A1MEN1KMT2AL3MBTL1
	SCHEMBL1564241	0.76	NR1H4 (0.55)	NR1H4ALDH1A1MEN1KMT2APRMT5
	SCHEMBL13754874	0.76	NR1H4 (0.55)	NR1H4ALDH1A1MEN1KMT2APRMT5
	SCHEMBL755250	0.76	NR1H4 (0.49)	NR1H4ALDH1A1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.