Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7622516 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL868273 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5702690 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7553779 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL3373653 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL3732235 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3734962 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL5702880 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL28900385 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL12816509 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426395-B1 | SUCH AS OXO-BIS-(DIMETHYLSILYLENE-BIS(2,3,5-TRIMETHYLCYCLOPENTADIENYL)ZIRCONIUM CHLORIDE); CRYSTALLIZATION/ CRYSTAL STRUCTURE | CHISSO CORPORATION (JP) | 2002-07-30 | — | — | US | disclosed |
| EP-0841349-B1 | Catalyst for alpha-olefin polymerization and production of poly-alpha-olefin therewith | MITSUI CHEMICALS INC (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |
| US-6121394-A | Metallocene-catalyzed olefin polymerization in the absence of aluminoxane | MITSUI CHEMICALS, INC. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0500944-B1 | CATALYST FOR ALPHA-OLEFIN POLYMERIZATION AND PRODUCTION OF POLY-ALPHA-OLEFIN THEREWITH | MITSUI CHEMICALS INC (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0841349-A2 | Catalyst for alpha-olefin polymerization and production of poly-alpha-olefin therewith | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0500944-A1 | CATALYST FOR $g(a)-OLEFIN POLYMERIZATION AND PRODUCTION OF POLY-$g(a)-OLEFIN THEREWITH | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-09-02 | — | — | EP | disclosed |