Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 8/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7553137 | 1.00 | ESR2 (0.39) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL8727559 | 0.96 | ESR2 (0.41) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL8727564 | 0.96 | ESR2 (0.41) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL7912624 | 0.85 | ESR2 (0.41) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL7912629 | 0.85 | ESR2 (0.41) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL7741316 | 0.84 | ESR2 (0.44) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL10864824 | 0.84 | NPC1 (0.47) | ESR2DGAT1CYP2C9NPC1RAB9A | |
| SCHEMBL7741318 | 0.84 | ESR2 (0.44) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL8038575 | 0.82 | ESR2 (0.41) | ESR2DGAT1CYP2C9ALDH1A1LMNA | |
| SCHEMBL8034648 | 0.82 | ESR2 (0.41) | ESR2DGAT1CYP2C9ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844248-B1 | Crosslinkable, photoactive silane derivatives | ROLIC AG (CH) | 2002-07-10 | — | — | EP | disclosed |
| US-5965761-A | CROSSLINKABLE SILANE DERIVAATIVES HAVING A 3-ARYLACRYLIC ACID OR-ACRYLAMIDE GROUP FOR ORIENTING LAYER AND FOR NONSTRUCTURED AND STRUCTURED OPTICAL ELEMENTS AND MULTILAYER SYSTEMS; PHOTOSTABILITY; CONTRAST; RESOLUTION | ROLIC AG (CH) | 1999-10-12 | — | — | US | disclosed |
| EP-0844248-A2 | Crosslinkable, photoactive silane derivatives | Rolic AG (CH) | 1998-05-27 | — | — | EP | disclosed |