Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 6/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.40 |
| ▸ | KDM5A | P29375 | 6/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558693 | 1.00 | EPHX2 (0.47) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL7555480 | 1.00 | EPHX2 (0.47) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL7552637 | 1.00 | EPHX2 (0.47) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL5206157 | 0.92 | ALDH1A1 (0.45) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL7559173 | 0.91 | EPHX2 (0.54) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL7556509 | 0.91 | EPHX2 (0.54) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL7554568 | 0.91 | EPHX2 (0.54) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL7559535 | 0.91 | EPHX2 (0.54) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL7555063 | 0.91 | EPHX2 (0.54) | EPHX2ALDH1A1BCHEACHECNR1 | |
| SCHEMBL8778605 | 0.89 | EPHX2 (0.60) | EPHX2ALDH1A1BCHEACHECNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |