Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6697596 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL137881 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL820388 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL4728578 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6908379 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL674165 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL7913314 | 0.69 | SCN1A (0.32) | — | |
| Hydrochloric Acid SCHEMBL712477 | 0.68 | NPC1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL716978 | 0.68 | KCNK9 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7913319 | 0.68 | MEN1 (0.41) | CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002038634-A2 | POLYPROPYLENE HAVING LOW ISOTACTICITY AND RELATIVELY HIGH MELTING POINT | BASELL POLYOLEFINE GMBH (DE) | 2002-05-16 | — | — | WO | disclosed |