Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.55 |
| ▸ | PARP1 | P09874 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 3/20 | 0.50 |
| ▸ | SI | P14410 | 3/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CBFB | Q13951 | 2/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969470 | 0.87 | DHODH (0.52) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL28027630 | 0.87 | HPSE (0.65) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL29625822 | 0.87 | HPSE (0.65) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL7261542 | 0.83 | DHODH (0.49) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL31027957 | 0.79 | DHODH (0.59) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL10695579 | 0.77 | PDE5A (0.57) | DHODHPARP1GAAMGAMSI | |
| SCHEMBL24067330 | 0.77 | DHODH (0.58) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL5565092 | 0.77 | PARP1 (0.60) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL7146754 | 0.77 | DHODH (0.62) | DHODHPARP1GAANPC1RAB9A | |
| SCHEMBL56853 | 0.77 | PARP1 (0.62) | DHODHPARP1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002060374-A2 | BENZ-1,3-AZOLE DERIVATIVES AND THEIR USES AS HEPARANASE INHIBITORS | INSIGHT STRATEGY AND MARKETING LTD (IL) | 2002-08-08 | — | — | WO | disclosed |