Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 5/20 | 0.57 |
| ▸ | PDE4A | P27815 | 4/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.57 |
| ▸ | CBFB | Q13951 | 2/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GNRHR | P30968 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695582 | 0.80 | PDE5A (0.46) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28027630 | 0.78 | HPSE (0.65) | CBFBCYP2D6ALDH1A1TP53CYP3A4 | |
| SCHEMBL29625822 | 0.78 | HPSE (0.65) | CBFBCYP2D6ALDH1A1TP53CYP3A4 | |
| SCHEMBL7553357 | 0.77 | DHODH (0.55) | CBFBCYP2D6ALDH1A1TP53CYP3A4 | |
| SCHEMBL3969470 | 0.75 | DHODH (0.52) | CBFBCYP2D6ALDH1A1TP53CYP3A4 | |
| SCHEMBL7261542 | 0.74 | DHODH (0.49) | CBFBCYP2D6ALDH1A1TP53CYP3A4 | |
| SCHEMBL27723388 | 0.74 | MCHR1 (0.55) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5970048 | 0.73 | DHODH (0.58) | ALDH1A1TP53CYP3A4ALOX15DHODH | |
| SCHEMBL38656506 | 0.73 | PDE5A (0.72) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9320573 | 0.73 | ATP4A (0.74) | DRD2DRD3ALDH1A1SMN1; SMN2ATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251760-A2 | Rubber composition | Bridgestone Corporation (JP) | 1988-01-07 | — | — | EP | disclosed |