Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22616347 | 0.91 | FAAH (0.61) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL12934924 | 0.89 | FAAH (0.83) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL12934930 | 0.89 | FAAH (0.83) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL12934928 | 0.89 | FAAH (0.83) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL12934925 | 0.87 | FAAH (0.78) | FAAHMEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL7555477 | 0.82 | FAAH (0.52) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL7552630 | 0.82 | FAAH (0.52) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL7558688 | 0.82 | FAAH (0.52) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL7553234 | 0.82 | FAAH (0.52) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL7343969 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |