Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 6/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601667 | 0.76 | COMT (0.77) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| SCHEMBL5033149 | 0.76 | TTR (0.43) | COMTCYP1A2NSD2 | |
| SCHEMBL114961 | 0.76 | COMT (1.00) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| SCHEMBL29456746 | 0.76 | COMT (1.00) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| SCHEMBL4624672 | 0.75 | COMT (0.75) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| Lithium SCHEMBL4624679 | 0.75 | COMT (0.75) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| SCHEMBL9407080 | 0.74 | COMT (0.97) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| Water SCHEMBL10628327 | 0.74 | COMT (0.97) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| SCHEMBL11317138 | 0.74 | COMT (0.97) | COMTCYP1A2HIF1AALOX15HSD17B10 | |
| SCHEMBL1873349 | 0.74 | COMT (0.97) | COMTCYP1A2HIF1AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002060374-A2 | BENZ-1,3-AZOLE DERIVATIVES AND THEIR USES AS HEPARANASE INHIBITORS | INSIGHT STRATEGY AND MARKETING LTD (IL) | 2002-08-08 | — | — | WO | disclosed |