Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.64 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
| ▸ | FNTB | P49356 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25676 | 0.91 | CES1 (0.64) | PLA2G10PLA2G2ACA2CES2CES1 | |
| SCHEMBL19307821 | 0.91 | CA2 (0.70) | PLA2G10PLA2G2ACA2KMT2A | |
| Phosphine SCHEMBL29287353 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 | |
| Hydrochloric Acid SCHEMBL1621316 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 | |
| Water SCHEMBL27968188 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 | |
| Hydrochloric Acid SCHEMBL29642911 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 | |
| Hydrochloric Acid SCHEMBL3651517 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 | |
| SCHEMBL4165526 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 | |
| Methane SCHEMBL2335788 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 | |
| SCHEMBL3927471 | 0.89 | CES1 (0.61) | PLA2G10PLA2G2ACA2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104419921-B | A kind of water-soluble silver protecting agent and preparation method thereof, chemical silver plating method and electroplate workpiece | 比亚迪股份有限公司 | 2017-07-21 | — | — | CN | claimed |
| CN-104419921-B | A kind of water-soluble silver protecting agent and preparation method thereof, chemical silver plating method and electroplate workpiece | 比亚迪股份有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-106380418-A | Method for efficiently rearranging ketoxime Beckmann by N-methyl pyrrolidone/SOC12 (thionyl chloride) | 上饶师范学院 | 2017-02-08 | — | — | CN | disclosed |
| WO-2010039256-A1 | 2-ACYLAMINOPROPOANOL-TYPE GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2010-04-08 | — | — | WO | disclosed |
| EP-0946495-B1 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| US-6353128-B1 | FOR TREATMENT OF CONDITIONS SUCH AS SEPTIC SHOCK. | ELI LILLY AND COMPANY | 2002-03-05 | — | — | US | disclosed |
| EP-0946495-A4 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | LILLY CO ELI (US) | 2000-04-12 | — | — | EP | disclosed |
| EP-0946495-A1 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024756-A1 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |