Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenylphosphonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.80 |
| ▸ | CA4 | P22748 | 1/20 | 0.80 |
| ▸ | CA5A | P35218 | 1/20 | 0.80 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylphosphonic Acid SCHEMBL9003185 | 0.90 | CA2 (0.89) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL269853 | 0.89 | CA2 (1.00) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL34998 | 0.89 | CA2 (1.00) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL28151870 | 0.89 | CA2 (1.00) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL753672 | 0.89 | CA2 (0.70) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL755159 | 0.89 | CA2 (0.70) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL752758 | 0.89 | CA2 (0.70) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL755088 | 0.89 | CA2 (0.70) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL753534 | 0.89 | CA2 (0.70) | CA2CA4CA5ACFTRTSHR | |
| Phenylphosphonic Acid SCHEMBL9709478 | 0.87 | CA2 (0.84) | CA2CA4CA5ACFTRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476372-B2 | Polyester fiber and method for its production, and tire cord, tire, belt-reinforcing fiber material and belt comprising the polyester fiber | TEIJIN FIBERS LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| EP-2261403-B1 | POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER | TEIJIN FIBERS LTD (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-20110017378-A1 | POLYESTER FIBER AND METHOD FOR ITS PRODUCTION, AND TIRE CORD, TIRE, BELT-REINFORCING FIBER MATERIAL AND BELT COMPRISING THE POLYESTER FIBER | TEIJIN FIBERS LIMITED (JP) | 2011-01-27 | — | — | US | disclosed |
| EP-2261403-A1 | POLYESTER FIBER, PROCESS FOR PRODUCING THE POLYESTER FIBER, AND TIRE CODE, TIRE, FIBER MATERIAL FOR REINFORCING BELT AND BELT EACH COMPRISING THE POLYESTER FIBER | Teijin Fibers Limited (JP) | 2010-12-15 | — | — | EP | disclosed |