SCHEMBL7554680

SCHEMBL7554680

CC(C)(C)OC(=O)NCC(=O)NCC(CNC(=O)CNC(=O)OC(C)(C)C)(CNC(=O)CNC(=O)OC(C)(C)C)CNC(=O)CNC(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.44
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GAA P10253 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
CA2 P00918 4/20 0.40
CA1 P00915 4/20 0.40
CA7 P43166 2/20 0.40
NPFFR1 Q9GZQ6 1/20 0.38
NPFFR2 Q9Y5X5 1/20 0.38
CA12 O43570 4/20 0.38
CA14 Q9ULX7 2/20 0.38
APLNR P35414 1/20 0.38
CA9 Q16790 2/20 0.37
EPHX1 P07099 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18282472 0.93 MEN1 (0.41) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL19178271 0.89 TDP1 (0.44) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL13678549 0.89 TDP1 (0.44) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL23655994 0.87 KMT2A (0.38) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL23350894 0.87 TDP1 (0.43) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL24503827 0.87 TDP1 (0.47) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL23465643 0.85 TDP1 (0.42) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL1289840 0.85 TDP1 (0.42) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL18843239 0.84 MEN1 (0.42) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL3984277 0.82 TDP1 (0.46) TDP1MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104409-A1 MULTIMERIC MANGANESE CONTRAST AGENTS BAYER AKTIENGESELLSCHAFT (DE) 2026-05-21 WO disclosed
EP-4741400-A1 MULTIMERIC MANGANESE CONTRAST AGENTS Bayer Aktiengesellschaft (DE) 2026-05-13 EP disclosed
US-12478696-B2 Gadolinium chelate compounds for use in magnetic resonance imaging BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-11-25 US disclosed
US-20250114485-A1 GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-04-10 US disclosed
US-20230113481-A1 NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2023-04-13 US disclosed
US-11491245-B2 Gadolinium chelate compounds for use in magnetic resonance imaging BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-11-08 US disclosed
US-11491245-B2 Gadolinium chelate compounds for use in magnetic resonance imaging BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2022-11-08 US disclosed
CN-107667096-B Novel gadolinium chelate compounds for magnetic resonance imaging 拜耳医药股份公司 2021-02-02 CN disclosed
US-20200353104-A1 GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2020-11-12 US disclosed
US-10722601-B2 Gadolinium chelate compounds for use in magnetic resonance imaging BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2020-07-28 US disclosed
US-20190083659-A1 GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-03-21 US disclosed
US-20180169274-A1 NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2018-06-21 US disclosed
WO-2016193190-A1 NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-12-08 WO disclosed
EP-0863769-B1 GLYCOCONJUGATES AS VIRUS CELL ADHESION INHIBITORS SYNTESOME GES FUR MED BIOCHEMI (DE) 2002-07-03 EP disclosed
EP-0863769-A1 GLYCOCONJUGATES AS VIRUS CELL ADHESION INHIBITORS Syntesome Gesellschaft Fur Med. Biochemie M.B.H. (DE) 1998-09-16 EP disclosed
EP-0863769-A2 GLYCOCONJUGATES AS VIRUS CELL ADHESION INHIBITORS Syntesome Gesellschaft Fur Med. Biochemie M.B.H. (DE) 1998-09-16 EP disclosed
WO-1998014215-A2 GLYCOCONJUGATES AS VIRUS CELL ADHESION INHIBITORS SYNTESOME GESELLSCHAFT FÜR MED. BIOCHEMIE M.B.H. (DE) 1998-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12478696-B2 Gadolinium chelate compounds for use in magnetic resonance imaging GLRA1, GLRA3, GLRB TDP1 1272/4885MAOA 4652/4885MAOB 4339/4885
US-10722601-B2 Gadolinium chelate compounds for use in magnetic resonance imaging GLRA1, GLRA3, GLRB TDP1 1432/4885MAOA 4794/4885MAOB 4639/4885
US-11491245-B2 Gadolinium chelate compounds for use in magnetic resonance imaging GLRA1, GLRA3, GLRB TDP1 1202/4885MAOA 4733/4885MAOB 4477/4885
US-20230113481-A1 NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING GLRA1, GLRA3, GLRB TDP1 1345/4885MAOA 4619/4885MAOB 4275/4885
US-20180169274-A1 NEW GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING RXFP1, MAG, GLRX3 TDP1 1709/4885MAOA 4208/4885MAOB 3745/4885
US-20200353104-A1 GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING GLRA1, GLRA3, GLRB TDP1 1202/4885MAOA 4733/4885MAOB 4477/4885
US-20250114485-A1 GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING GLRA1, GLRA3, GLRB TDP1 1272/4885MAOA 4652/4885MAOB 4339/4885
US-20190083659-A1 GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING GLRA1, GLRA3, GLRB TDP1 1432/4885MAOA 4794/4885MAOB 4639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.