Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23465643 | 0.89 | TDP1 (0.42) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL4202727 | 0.87 | TDP1 (0.48) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL7554680 | 0.85 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL13678549 | 0.85 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL19178271 | 0.85 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL24503827 | 0.84 | TDP1 (0.47) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL23350894 | 0.84 | TDP1 (0.43) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL20050532 | 0.83 | TDP1 (0.44) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL15805765 | 0.83 | TDP1 (0.47) | TDP1MAOAMAOBMEN1KMT2A | |
| SCHEMBL18843239 | 0.81 | MEN1 (0.42) | TDP1MAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-07-17 | — | — | US | disclosed |
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | CORTEVA AGRISCIENCE LLC (US) | 2024-04-02 | — | — | US | disclosed |
| US-20230303482-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY | 2023-09-28 | — | — | US | disclosed |
| US-20230303482-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY | 2023-09-28 | — | — | US | disclosed |
| EP-3150575-B1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | DU PONT (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3150575-B1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | DU PONT (US) | 2023-08-09 | — | — | EP | disclosed |
| US-11613516-B2 | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2023-03-28 | — | — | US | disclosed |
| CN-115536541-A | Synthesis method of common intermediate of flurradine and afurane | 湖北美天生物科技股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| EP-3971166-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Corteva Agriscience LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| EP-3971166-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Corteva Agriscience LLC (US) | 2022-03-23 | — | — | EP | disclosed |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-10 | — | — | US | disclosed |
| EP-2621894-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. Du Pont De Nemours And Company (US) | 2013-08-07 | — | — | EP | disclosed |
| US-20130131053-A1 | ISOXAZOLINE DERIVATIVES AS PESTICIDES | NOVARTIS TIERGESUNDHEIT AG (CH) | 2013-05-23 | — | — | US | disclosed |
| US-8383659-B2 | Isoxazoline derivatives as pesticides | NOVARTIS AG (CH) | 2013-02-26 | — | — | US | disclosed |
| EP-2379537-B1 | Isoxazoline derivatives and their use as pesticide | NOVARTIS AG (CH) | 2012-10-31 | — | — | EP | disclosed |
| WO-2012107533-A1 | ISOXAZOLINE DERIVATIVES FOR CONTROLLING INVERTEBRATE PESTS | NOVARTIS AG (CH) | 2012-08-16 | — | — | WO | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2012047543-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-12 | — | — | WO | disclosed |
| US-20110245239-A1 | ORGANIC COMPOUNDS | ELANCO TIERGESUNDHEIT AG (CH) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303482-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | NAAA, SAT1, NAA15 | TDP1 1121/4885MAOA 197/4885MAOB 399/4885 |
| US-11944099-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | ACHE, DDT, MLYCD | TDP1 683/4885MAOA 539/4885MAOB 998/4885 |
| US-20130131053-A1 | ISOXAZOLINE DERIVATIVES AS PESTICIDES | CYP3A7, ACHE, CYP4X1 | TDP1 2683/4885MAOA 1426/4885MAOB 1784/4885 |
| US-11613516-B2 | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl) acetamide | NAAA, SAT1, NAA15 | TDP1 1013/4885MAOA 174/4885MAOB 371/4885 |
| US-20250228239-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MLYCD | TDP1 683/4885MAOA 539/4885MAOB 998/4885 |
| US-20110245239-A1 | ORGANIC COMPOUNDS | ACHE, VDAC1, VDAC2 | TDP1 1361/4885MAOA 282/4885MAOB 396/4885 |
| US-20130267729-A1 | METHOD FOR PREPARING 2-AMINO-N-(2,2,2-TRIFLUOROETHYL) ACETAMIDE | NAAA, SAT1, NAA15 | TDP1 1013/4885MAOA 174/4885MAOB 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.