Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027873 | 0.78 | MAOA (0.46) | CES1CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29795069 | 0.78 | MAOA (0.46) | CES1CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL19645160 | 0.77 | CES1 (0.46) | CES1CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL22810220 | 0.77 | CES1 (0.46) | CES1CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7986644 | 0.77 | CES1 (0.46) | CES1CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL24287303 | 0.77 | CES1 (0.46) | CES1CYP17A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8534624 | 0.77 | CES1 (0.46) | CES1CYP17A1CYP19A1CYP11B1CYP11B2 | |
| Dihydrophenanthrene SCHEMBL155991 | 0.76 | CES1 (0.68) | CES1CYP19A1CYP11B1CYP11B2SETD7 | |
| Dihydrophenanthrene SCHEMBL29404495 | 0.76 | CES1 (0.68) | CES1CYP19A1CYP11B1CYP11B2SETD7 | |
| Dihydrophenanthrene SCHEMBL30297028 | 0.76 | CES1 (0.68) | CES1CYP19A1CYP11B1CYP11B2SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351074-B1 | Preparation of a dimethyltetralin | AMOCO CORP (US) | 1994-09-07 | — | — | EP | claimed |
| CN-108137508-A | 5-HT2CReceptor agonists and compositions and methods of use | 艾尼纳制药公司 | 2018-06-08 | — | — | CN | disclosed |
| EP-0996608-B1 | METHOD OF MAKING 2,6-DIMETHYLNAPHTHALENE FROM OTHER DIMETHYLNAPHTHALENE ISOMERS AND FROM DIMETHYLTETRALINS/DIMETHYLDECALINS WITH A METHYL GROUP ON EACH RING | CHEVRON PHILLIPS CHEMICAL CO (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-0996608-A1 | METHOD OF MAKING 2,6-DIMETHYLNAPHTHALENE FROM OTHER DIMETHYLNAPHTHALENE ISOMERS AND FROM DIMETHYLTETRALINS/DIMETHYLDECALINS WITH A METHYL GROUP ON EACH RING | Chevron Chemical Company LLC (US) | 2000-05-03 | — | — | EP | disclosed |
| US-4137419-A | FROM AN INDENE OR DIHYDRONAPHTHALENE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-3946081-A | OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | disclosed |