Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037181 | 0.82 | MAOB (0.43) | ROCK1PTK2GAAMAPTKMT2A | |
| SCHEMBL6660146 | 0.79 | HSP90AA1 (0.43) | ROCK1PTK2KMT2AKDM4ELMNA | |
| SCHEMBL31116815 | 0.79 | ROCK1 (0.51) | ROCK1L3MBTL1POLBHTR6PDGFRB | |
| SCHEMBL28842817 | 0.79 | ROCK1 (0.48) | ROCK1L3MBTL1POLBHTR6PDGFRB | |
| SCHEMBL1270502 | 0.79 | MAT2A (0.44) | PTK2GAAMEN1KMT2AKDM4E | |
| SCHEMBL31454935 | 0.79 | ROCK1 (0.54) | ROCK1L3MBTL1POLBHTR6PDGFRB | |
| SCHEMBL30097476 | 0.78 | BIRC5 (0.43) | ROCK1PTK2MEN1KMT2AKDM4E | |
| SCHEMBL699112 | 0.78 | BIRC5 (0.43) | ROCK1PTK2MEN1KMT2AKDM4E | |
| SCHEMBL16383852 | 0.76 | KMT2A (0.43) | PTK2L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL4580723 | 0.75 | ROCK1 (0.43) | ROCK1L3MBTL1POLBHTR6PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165512-A2 | METHOD FOR ARYLATING AZA-HETEROCYCLES WITH ACTIVATED AROMATIC COMPOUNDS IN THE PRESENCE OF CESIUM CARBONATE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059883-A2 | METHOD FOR PRODUCING N-ARYL-AZA-HETEROCYCLES IN THE PRESENCE OF CESIUM CARBONATE | Gödecke GmbH (DE) | 2000-10-12 | — | — | WO | disclosed |