⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755510 | 1.00 | — | — | |
| SCHEMBL11549692 | 0.85 | KMT2A (0.50) | — | |
| SCHEMBL11549688 | 0.85 | KMT2A (0.50) | — | |
| SCHEMBL11547598 | 0.82 | SQLE (0.38) | — | |
| SCHEMBL11547600 | 0.82 | SQLE (0.38) | — | |
| SCHEMBL7516148 | 0.78 | — | — | |
| SCHEMBL2019873 | 0.78 | — | — | |
| SCHEMBL2019871 | 0.78 | — | — | |
| SCHEMBL9808283 | 0.77 | — | — | |
| SCHEMBL28241054 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532390-B1 | Pharmaceutical composition for liver diseases. | MD BIOALPHA CO LTD (KR) | 2016-08-17 | — | — | EP | disclosed |
| US-9066922-B2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | MD BIOALPHA CO., LTD. (KR) | 2015-06-30 | — | — | US | disclosed |
| US-20130245111-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | KT & G CO., LTD. (KR) | 2013-09-19 | — | — | US | disclosed |
| EP-1848432-B1 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | MD BIOALPHA CO LTD (KR) | 2013-07-17 | — | — | EP | disclosed |
| US-8466141-B2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | MD BIOALPHA CO., LTD. (KR) | 2013-06-18 | — | — | US | disclosed |
| EP-2532388-A2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |
| EP-2532390-A2 | Pharmaceutical composition for obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |
| EP-2532389-A2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |
| US-8211904-B2 | Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease | Merck, Sharp & Dohme Corp. (US) | 2012-07-03 | — | — | US | disclosed |
| US-20120114714-A1 | METHOD FOR THE TREATMENT AND PREVENTION OF ERECTILE DYSFUNCTION | KWAK TAEHWAN (KR) | 2012-05-10 | — | — | US | disclosed |
| WO-2000051977-A1 | ALDEHYDE INTERMEDIATES FOR THE PREPARATION OF PROSTAGLANDIN DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-1012138-A1 | A PROCESS FOR MAKING EPOXIDE INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| US-6066751-A | Process for making epoxide intermediates | THE PROCTER & GAMBLE COMPANY (US) | 2000-05-23 | — | — | US | disclosed |
| WO-1999012897-A1 | A PROCESS FOR MAKING EPOXIDE INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 1999-03-18 | — | — | WO | disclosed |
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4561862-A | Use of selected beta-nitroalkenes as cetane number boosters for diesel fuel | OLIN CORPORATION (US) | 1985-12-31 | — | — | US | disclosed |
| US-4123556-A | Insecticidal composition | CIBA-GEIGY CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4061683-A | INSECTICIDE, MITICIDE | CIBA-GEIGY CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
| US-3998855-A | INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |