SCHEMBL7555141

SCHEMBL7555141

O=C1CN(c2ccccc2)C(=O)N1O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
CTSG P08311 14/20 0.51
CMA1 P23946 13/20 0.51
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9834330 0.77 KMT2A (0.61) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL151557 0.77 MEN1 (0.56) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL6363201 0.76 NPC1 (0.67) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL6107438 0.75 NPC1 (0.54) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL992528 0.75 MEN1 (0.54) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL2536250 0.75 NPC1 (0.54) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL2140322 0.75 MEN1 (0.54) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL28064367 0.75 MEN1 (0.54) NPC1RAB9AKMT2AMEN1CTSG
Ammonia Solution, Strong SCHEMBL9013686 0.73 MEN1 (0.52) NPC1RAB9AKMT2AMEN1CTSG
SCHEMBL921684 0.73 NPC1 (0.51) NPC1RAB9AKMT2AMEN1CTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-218296678-U Oven steam waste heat use system is used in production of hydroxybenzene hydantoin 内蒙古天宇达生物科技有限公司(CN) 2023-01-13 CN claimed
CN-213687641-U Drying device that turns is used in production of p hydroxy phenyl hydantoin 宣城菁科生物科技有限公司 2021-07-13 CN claimed
CN-213493313-U Mixing arrangement is used in production of p hydroxy phenyl hydantoin 宣城菁科生物科技有限公司 2021-06-22 CN claimed
CN-213133173-U Concentration kettle for DL-p-hydroxyphenylhydantoin production 定陶三化药业有限公司 2021-05-07 CN claimed
CN-212987778-U Drying equipment of DL-p-hydroxybenzene hydantoin production usefulness 定陶三化药业有限公司 2021-04-16 CN claimed
WO-1991009020-A2 PRODUCTION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-p-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE HOECHST CELANESE CORPORATION (US) 1991-06-27 WO claimed
EP-0070389-B1 2-(2-FLUORO-4-HALO-5-SUBSTITUTED PHENYL) HYDANTOINS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-02 EP claimed
EP-0070389-A2 2-(2-Fluoro-4-halo-5-substituted phenyl) hydantoins, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-26 EP claimed
CN-119707825-A Crystal form of p-hydroxy phenylhydantoin and preparation method thereof 合肥菁科生物科技有限公司 2025-03-28 CN disclosed
CN-218296678-U Oven steam waste heat use system is used in production of hydroxybenzene hydantoin 内蒙古天宇达生物科技有限公司(CN) 2023-01-13 CN disclosed
CN-213687641-U Drying device that turns is used in production of p hydroxy phenyl hydantoin 宣城菁科生物科技有限公司 2021-07-13 CN disclosed
CN-213687641-U Drying device that turns is used in production of p hydroxy phenyl hydantoin 宣城菁科生物科技有限公司 2021-07-13 CN disclosed
CN-213493313-U Mixing arrangement is used in production of p hydroxy phenyl hydantoin 宣城菁科生物科技有限公司 2021-06-22 CN disclosed
CN-213493313-U Mixing arrangement is used in production of p hydroxy phenyl hydantoin 宣城菁科生物科技有限公司 2021-06-22 CN disclosed
WO-2001019982-A2 MICRO-ORGANISMS, THEIR USE AND METHOD FOR PRODUCING D-AMINO ACIDS SA BIOPRODUCTS (PROPRIETARY) LIMITED (ZA) 2001-03-22 WO disclosed
WO-1991009020-A2 PRODUCTION OF 5-(4'-HYDROXYPHENYL)HYDANTOIN AND D-p-HYDROXYPHENYLGLYCINE FROM 4-HYDROXYACETOPHENONE HOECHST CELANESE CORPORATION (US) 1991-06-27 WO disclosed
EP-0070389-B1 2-(2-FLUORO-4-HALO-5-SUBSTITUTED PHENYL) HYDANTOINS, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-10-02 EP disclosed
US-4437877-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-03-20 US disclosed
EP-0070389-A2 2-(2-Fluoro-4-halo-5-substituted phenyl) hydantoins, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-01-26 EP disclosed
EP-0001319-A1 Process for the preparation of hydroxyphenyl hydantoin and of hydroxyphenyl glycine, and compounds thus obtained BEECHAM GROUP PLC (GB) 1979-04-04 EP disclosed