SCHEMBL992528

SCHEMBL992528

O=C1CN(c2ccccc2)C(=O)N1c1ccccc1.[NaH]

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
ALDH1A1 P00352 1/20 0.53
CTSG P08311 8/20 0.51
CMA1 P23946 7/20 0.51
ENPP2 Q13822 1/20 0.50
MGLL Q99685 1/20 0.45
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL151557 0.98 MEN1 (0.56) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL2140322 0.96 MEN1 (0.54) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL28064367 0.96 MEN1 (0.54) MEN1KMT2ANPC1RAB9AALDH1A1
Ammonia Solution, Strong SCHEMBL9013686 0.94 MEN1 (0.52) MEN1KMT2ANPC1RAB9AALDH1A1
Tetramethylammonium Ion SCHEMBL5964868 0.90 MEN1 (0.48) MEN1KMT2ANPC1RAB9AALDH1A1
Sulfuric Acid SCHEMBL27724452 0.89 CTSG (0.54) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL16315766 0.89 ENPP2 (0.60) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL29847310 0.87 KMT2A (0.49) MEN1KMT2ANPC1RAB9AALDH1A1
SCHEMBL11142249 0.84 CMA1 (0.59) KMT2ANPC1RAB9AALDH1A1CTSG
SCHEMBL15014093 0.83 KMT2A (0.57) MEN1KMT2ANPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104030637-B A kind of bamboo-carbon fibre concrete material and preparation method thereof ZHEJIANG COLLEGE OF CONSTRUCTION (CN) 2016-04-13 CN claimed
CN-104072037-B A kind of carbon nanotubes concrete and preparation method thereof BENGBU EAST CHINA GYPSUM CO., LTD. (CN) 2016-02-10 CN claimed
CN-105271957-A High strength concrete member and preparation method thereof TIANJIN MENGLOU XINLI TECHNOLOGY CO LTD 2016-01-27 CN claimed
CN-104628319-A Water-permeable concrete containing river sludge powder and concrete brick ZHEJIANG COLLEGE CONSTRUCTION 2015-05-20 CN claimed
CN-104072037-A Carbon nano-tube contained concrete and preparation method thereof BENGBU EAST CHINA GYPSUM CO LTD 2014-10-01 CN claimed
CN-104030637-A Bamboo charcoal fiber concrete material and preparation method thereof ZHEJIANG COLLEGE CONSTRUCTION 2014-09-10 CN claimed
CN-102531446-B Cement additive for municipal works and high-rise buildings GUANGDONG ZHONGJIANG ENGINEERING CONSTRUCTION CO LTD 2013-01-16 CN claimed
CN-102531446-A Cement additive for municipal works and high-rise buildings GUANGDONG ZHONGJIANG ENGINEERING CONSTRUCTION CO LTD 2012-07-04 CN claimed
US-RE37382-E1 Gum pad for mucosal delivery of medication YATES ALAYNE (US) 2001-09-18 US claimed
US-5741500-A ORAL APPLIANCE YATES ALAYNE (US) 1998-04-21 US claimed
CN-116069956-B Drug knowledge graph entity alignment method and device based on mixed attention mechanism 之江实验室 2023-07-04 CN disclosed
CN-116069956-A Drug knowledge graph entity alignment method and device based on mixed attention mechanism 之江实验室 2023-05-05 CN disclosed
US-20210009682-A1 REDUCING CUTANEOUS SCAR FORMATION AND TREATING SKIN CONDITIONS NORTHWESTERN UNIVERSITY 2021-01-14 US disclosed
US-20190225684-A1 REDUCING CUTANEOUS SCAR FORMATION AND TREATING SKIN CONDITIONS NORTHWESTERN UNIVERSITY 2019-07-25 US disclosed
CN-106498722-A A kind of 2,4 imidazolidimedione sodium salt compounding BTCA Fabric Wrinkle Resistant Finish agent of 5,5 diphenyl 佛山迅拓奥科技有限公司 2017-03-15 CN disclosed
US-4213893-A Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays MILES LABORATORIES, INC. (US) 1980-07-22 US disclosed
US-4212805-A INTERMEDIATES OF PHTHALHYDRAZIDE-LABELED CONJUGATES MILES LABORATORIES, INC. (US) 1980-07-15 US disclosed
US-4160818-A Fluorimetric immunoassay for diphenylhydantoin TECHNICON INSTRUMENTS CORPORATION (US) 1979-07-10 US disclosed
US-4110461-A EFFECT OF DIPHENYLHYDANTOIN AND RELATED COMPOUNDS ON GLAUCOMA THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) 1978-08-29 US disclosed
US-4046894-A Certain barbituric acid derivatives used as anticonvulsant agents BRISTOL-MYERS COMPANY (US) 1977-09-06 US disclosed