Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 8/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921111 | 0.89 | CSNK2A2 (0.53) | CSNK2A2CSNK2BCSNK2A1ABCG2FABP4 | |
| SCHEMBL6924568 | 0.82 | FABP4 (0.51) | CSNK2A2CSNK2BCSNK2A1ABCG2FABP4 | |
| SCHEMBL5830904 | 0.80 | DYRK1A (0.68) | DYRK1ABRD4 | |
| SCHEMBL6925034 | 0.77 | CSNK2A2 (0.54) | DYRK1ACSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6925466 | 0.76 | ATM (0.55) | CSNK2A2CSNK2BCSNK2A1ABCG2FABP4 | |
| SCHEMBL6691727 | 0.74 | FABP4 (0.74) | CSNK2A2CSNK2BCSNK2A1ABCG2FABP4 | |
| SCHEMBL6923369 | 0.72 | FABP4 (0.50) | DYRK1ACSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6685674 | 0.72 | FABP4 (0.74) | FABP4FABP3 | |
| SCHEMBL30480036 | 0.72 | HDAC1 (0.70) | CSNK2A2CSNK2BCSNK2A1ABCG2HDAC1 | |
| SCHEMBL6925178 | 0.72 | HDAC1 (0.70) | CSNK2A2CSNK2BCSNK2A1ABCG2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210329-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001017963-A2 | AMINOALKOXY CARBAZOLES AND THEIR USE AS 5-HT LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 2001-03-15 | — | — | WO | disclosed |