Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.49 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12407109 | 0.86 | CYP1A2 (0.73) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL3787132 | 0.86 | CYP1A2 (0.73) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL9175285 | 0.84 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL6333143 | 0.84 | MAPT (0.63) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL11025115 | 0.84 | SMN1; SMN2 (0.73) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL10631076 | 0.84 | KMT2A (0.69) | SMN1; SMN2KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL21695366 | 0.84 | KMT2A (0.58) | SMN1; SMN2KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL2765494 | 0.83 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL3102289 | 0.82 | KCNQ3 (0.62) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL30796328 | 0.82 | KCNQ3 (0.62) | CYP1A2CYP2C9CYP2C19SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002056681-A2 | NOVEL INTERMEDIATES AND PROCESS TO PYRIMIDINEDIONE HERBICIDES | FMC CORPORATION (US) | 2002-07-25 | — | — | WO | disclosed |
| US-5753595-A | Herbicidal 3-(substituted benzoxazol-7-yl) and 3-(Substituted benzothiazol-7-yl)-1-substituted-6-trifluoromethyl-2 4-(1h 3h)pyrimidinediones | FMC CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1997008170-A1 | HERBICIDAL 3-(SUBSTITUTED BENZOXAZOL-7-YL) AND 3-(SUBSTITUTED BENZOTHIAZOL-7-YL)-1-SUBSTITUTED-6-TRIFLUOROMETHYL-2,4-(1H,3H)PYRIMIDINEDIONES | FMC CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |
| US-4859229-A | HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1989-08-22 | — | — | US | disclosed |