Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616117 | 0.84 | KMT2A (0.52) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7555717 | 0.84 | CYP1A2 (0.58) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3785176 | 0.84 | HPGD (0.67) | KMT2AHPGDALDH1A1MEN1PKM | |
| SCHEMBL1503921 | 0.83 | KMT2A (0.55) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29683063 | 0.82 | KDM4E (0.62) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3873599 | 0.82 | KDM4E (0.62) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2015592 | 0.82 | HTT (0.62) | NPC1RAB9ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12407083 | 0.82 | HPGD (0.70) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2095473 | 0.82 | HPGD (0.58) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL19707984 | 0.82 | KMT2A (0.66) | KMT2ANPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10556889-B1 | Salvinorin derivatives | Blue Sky Pharmaceuticals, LLC (US) | 2020-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556889-B1 | Salvinorin derivatives | OPRD1, OPRK1, OPRL1 | KMT2A 3351/4885NPC1 1602/4885RAB9A 1009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.