Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | GPR4 | P46093 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1651553 | 0.82 | F10 (0.56) | F10KCNH2 | |
| SCHEMBL7559434 | 0.82 | F10 (0.49) | F10PI4KAPI4K2BPI4K2API4KB | |
| Hydrochloric Acid SCHEMBL4385581 | 0.81 | F10 (0.56) | F10KCNH2 | |
| SCHEMBL4397007 | 0.76 | F10 (0.47) | F10KCNH2 | |
| SCHEMBL7554775 | 0.69 | F10 (0.38) | F10HTR2C | |
| SCHEMBL7402683 | 0.68 | F10 (0.40) | F10GPR4KCNH2 | |
| SCHEMBL7542716 | 0.68 | F10 (0.56) | F10 | |
| SCHEMBL1652537 | 0.68 | F10 (0.66) | F10 | |
| SCHEMBL1652680 | 0.68 | F10 (0.34) | F10 | |
| Hydrochloric Acid SCHEMBL7375541 | 0.67 | F10 (0.55) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051176-A4 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARM PROD INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1051176-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037304-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-07-29 | — | — | WO | disclosed |