Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446984 | 0.92 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL4092996 | 0.91 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL7077870 | 0.88 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL5335179 | 0.86 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL7081904 | 0.86 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL7555635 | 0.85 | P2RX7 (0.72) | P2RX7 | |
| SCHEMBL7553805 | 0.85 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL7082380 | 0.85 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL7077648 | 0.85 | P2RX7 (0.66) | P2RX7 | |
| SCHEMBL6442061 | 0.85 | P2RX7 (0.56) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171432-A1 | ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000061569-A1 | ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2000-10-19 | — | — | WO | disclosed |