Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251829 | 0.89 | KDR (0.40) | KDR | |
| SCHEMBL7553518 | 0.78 | KDR (0.41) | CACNA1BKDRBCDIN3D | |
| SCHEMBL7554465 | 0.72 | KDR (0.43) | KDRBCDIN3D | |
| SCHEMBL7556842 | 0.71 | KDR (0.43) | KDRBCDIN3D | |
| SCHEMBL5251826 | 0.69 | KDR (0.65) | KDR | |
| SCHEMBL7550488 | 0.66 | KDR (0.43) | KDR | |
| SCHEMBL7550492 | 0.66 | KDR (0.43) | KDR | |
| SCHEMBL5253291 | 0.64 | KDR (0.48) | KDR | |
| SCHEMBL5250179 | 0.63 | FGFR1 (0.53) | KDR | |
| SCHEMBL5249048 | 0.63 | CHEK1 (0.49) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218348-A2 | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE | AGOURON PHARMACEUTICALS, INC. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001002369-A2 | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE | AGOURON PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |