Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 3/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL989052 | 1.00 | LMNA (0.67) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL7554998 | 1.00 | LMNA (0.67) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL7555392 | 1.00 | LMNA (0.67) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL7558507 | 1.00 | LMNA (0.67) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL5542370 | 1.00 | LMNA (0.67) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL498180 | 0.98 | LMNA (0.70) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL497604 | 0.91 | LMNA (0.73) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL13630657 | 0.89 | LMNA (0.84) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL3306771 | 0.86 | LMNA (0.89) | LMNAALDH1A1TSHRNPC1HPGD | |
| SCHEMBL18106721 | 0.86 | LMNA (0.54) | LMNAALDH1A1TSHRHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |