Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.84 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.74 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.74 |
| ▸ | CLK1 | P49759 | 1/20 | 0.74 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.74 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.74 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.70 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.68 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.67 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | NAT1 | P18440 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7556271 | 1.00 | PIK3CG (0.84) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL18102871 | 0.92 | PIK3CG (1.00) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL2633099 | 0.86 | ADAMTS5 (0.84) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL1726213 | 0.86 | ADAMTS5 (0.84) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL17140247 | 0.86 | ADAMTS5 (0.84) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL18102968 | 0.85 | PIK3CG (0.67) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL8312402 | 0.85 | CSNK2A2 (1.00) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL15421331 | 0.85 | CSNK2A2 (1.00) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL8312399 | 0.85 | CSNK2A2 (1.00) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B | |
| SCHEMBL5576612 | 0.84 | PIM1 (0.77) | PIK3CGDYRK1ACSNK2A2CLK1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062337-A1 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-15 | — | — | WO | claimed |
| WO-2002062337-A1 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-15 | — | — | WO | disclosed |
| US-5464856-A | Arylmethylenyl derivatives of imidazolidinones useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5306822-A | Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |