Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559743 | 0.86 | PDK2 (0.42) | ALDH1A1HSD17B10HPGDBCL2L1TOP1 | |
| SCHEMBL7552809 | 0.85 | TDP1 (0.43) | ALDH1A1HSD17B10HPGDLMNASMN1; SMN2 | |
| SCHEMBL15723950 | 0.83 | PTGS1 (0.44) | ALDH1A1HSD17B10HPGDBCL2L1TOP1 | |
| SCHEMBL2799553 | 0.82 | TOP1 (0.35) | ALDH1A1HSD17B10HPGDBCL2L1LMNA | |
| SCHEMBL7558423 | 0.81 | KDM4E (0.44) | ALDH1A1HSD17B10HPGDSMN1; SMN2MAPK1 | |
| SCHEMBL14555509 | 0.80 | PTGS2 (0.45) | ALDH1A1HSD17B10HPGDLMNATOP1 | |
| SCHEMBL2027276 | 0.78 | PTGS2 (0.47) | HPGDLMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27658148 | 0.77 | PTGS1 (0.40) | ALDH1A1HSD17B10LMNATOP1HTT | |
| SCHEMBL15723954 | 0.76 | PTGS2 (0.41) | ALDH1A1HSD17B10TOP1HTTCHRNB2 | |
| SCHEMBL20466883 | 0.76 | PTGS1 (0.39) | ALDH1A1HSD17B10HPGDLMNATOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036081-B1 | HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS | CIBA SC HOLDING AG (CH) | 2002-07-17 | — | — | EP | disclosed |
| US-6417363-B1 | POLYMERIZATION, RING-CLOSURE METATHESIS, OLIGOMERIZATION, AND CYCLIZATION CATALYSTS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-07-09 | — | — | US | disclosed |
| EP-1036081-A1 | HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS | Ciba SC Holding AG (CH) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029701-A1 | HETEROCYCLYL LIGAND CONTAINING RUTHENIUM AND OSMIUM CATALYSTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-06-17 | — | — | WO | disclosed |