Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125961 | 0.88 | GABRA1 (0.52) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL27921111 | 0.87 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL4000170 | 0.87 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL4966112 | 0.87 | GABRA1 (0.50) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL23581449 | 0.85 | GABRA1 (0.41) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL31577204 | 0.85 | GABRA1 (0.49) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL5824091 | 0.84 | GABRA1 (0.58) | GABRA1GABRB2AKR1B1L3MBTL1MEN1 | |
| SCHEMBL16487344 | 0.83 | GABRA1 (0.50) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL8653763 | 0.82 | FOLH1 (0.45) | GABRA1GABRB2AKR1B1AURKADAPK3 | |
| SCHEMBL17924772 | 0.82 | GABRA1 (0.40) | GABRA1GABRB2AKR1B1AURKADAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072651-A1 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2002-09-19 | — | — | WO | disclosed |