Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552344 | 0.96 | FFAR1 (0.55) | FFAR1PTGDR2PTGDRPPARGPPARA | |
| SCHEMBL7474979 | 0.86 | CYSLTR2 (0.57) | FFAR1PTGDR2PTGDRPPARGPPARA | |
| SCHEMBL7557832 | 0.83 | CYP2D6 (0.57) | — | |
| SCHEMBL10730356 | 0.83 | PLA2G4B (0.60) | FFAR1PTGDR2CYSLTR2CYSLTR1FFAR4 | |
| SCHEMBL10982703 | 0.82 | FFAR1 (0.56) | FFAR1PPARGPPARACYSLTR2CYSLTR1 | |
| SCHEMBL947863 | 0.82 | FFAR1 (0.67) | FFAR1PTGDR2PTGDRPPARGPPARA | |
| SCHEMBL17413767 | 0.82 | FFAR1 (0.71) | FFAR1CYSLTR2CYSLTR1FFAR4PPARD | |
| SCHEMBL7474657 | 0.81 | FFAR1 (0.62) | FFAR1PPARGPPARAFFAR4PPARD | |
| SCHEMBL7989273 | 0.81 | CYSLTR2 (0.54) | FFAR1PTGDR2PTGDRPPARGPPARA | |
| SCHEMBL11605768 | 0.81 | PPARA (0.54) | FFAR1PTGDR2PTGDRPPARACYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |