Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552622 | 0.96 | CYP2D6 (0.58) | CYP2D6KCNH2MAPK1PDK2 | |
| SCHEMBL4568886 | 0.87 | CYP2D6 (0.67) | CYP2D6KCNH2NPC1LMNAALOX15 | |
| SCHEMBL29818840 | 0.86 | CYP2D6 (0.56) | CYP2D6KCNH2NPC1LMNAALOX15 | |
| SCHEMBL2207909 | 0.86 | CYP2D6 (0.56) | CYP2D6KCNH2NPC1LMNAALOX15 | |
| SCHEMBL7556540 | 0.83 | FFAR1 (0.56) | — | |
| SCHEMBL10235907 | 0.83 | CYP2D6 (0.62) | CYP2D6KCNH2 | |
| SCHEMBL611282 | 0.82 | CYP2D6 (0.55) | CYP2D6KCNH2ACHE | |
| SCHEMBL27996248 | 0.82 | CYP2D6 (0.57) | CYP2D6KCNH2 | |
| SCHEMBL13959280 | 0.80 | ACHE (0.56) | CYP2D6KCNH2ACHE | |
| SCHEMBL2208406 | 0.80 | CYP2D6 (0.53) | CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |