Propylene Oxide

Propylene Oxide

SCHEMBL7556563

CC1CO1.CC1CO1.CC1CO1.CC1CO1.OCCO

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.37
CHRM5 P08912 2/20 0.37
CHRM3 P20309 2/20 0.37
CHRM4 P08173 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL168597 1.00
Propylene Oxide SCHEMBL9873297 1.00 CHRM2 (0.37) CHRM2CHRM5CHRM3CHRM4TSHR
Propylene Oxide SCHEMBL9874479 1.00 CHRM2 (0.37) CHRM2CHRM5CHRM3CHRM4TSHR
Propylene Oxide SCHEMBL4566848 0.91 CHRM2 (0.33) CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL2011522 0.91 CHRM2 (0.33) CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL8857935 0.88 CHRM2 (0.32) CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL8526540 0.87
1,4-Butanediol SCHEMBL11328788 0.87 SMN1; SMN2 (0.40) CHRM2CHRM5CHRM3CHRM4TSHR
Propylene Oxide SCHEMBL10391364 0.86 TDP1 (0.33) CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL16267581 0.86 CHRM2 (0.31) CHRM2CHRM5CHRM3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6441125-B2 IN MELT OF AN ALKYLENE GLYCOL, A POLYALKYLENE GLYCOL AND AN AROMATIC DICARBOXYLIC ACID; RATIO OF TITANIUM TO BIVALENT METAL IN THE CATALYST IS LOWER THAN 2; POLYCONDENSATION TIME IS SHORTENED; LESS CHAIN BRANCHING AGENTS DSM N. V. (NL) 2002-08-27 US claimed
US-20020016437-A1 In melt of an alkylene glycol, a polyalkylene glycol and an aromatic dicarboxylic acid; ratio of titanium to bivalent metal in the catalyst is lower than 2; polycondensation time is shortened; less chain branching agents DSM IP ASSETS B.V. (NL) 2002-02-07 US claimed
CN-1331712-A Preparation of Copolyether Ester DSM NV (NL) 2002-01-16 CN claimed
EP-1141076-A1 PREPARATION OF A COPOLYETHER ESTER DSM N.V. (NL) 2001-10-10 EP claimed
WO-2000024803-A1 PREPARATION OF A COPOLYETHER ESTER DSM N.V. (NL) 2000-05-04 WO claimed