Propylene Oxide

Propylene Oxide

SCHEMBL2011522

C1CO1.CC1CO1.OCCO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 3/20 0.33
CHRM5 P08912 3/20 0.33
CHRM3 P20309 3/20 0.33
CHRM4 P08173 2/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PDK1 Q15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL4566848 1.00 CHRM2 (0.33) CHRM2CHRM5CHRM3CHRM4KDM4E
Propylene Oxide SCHEMBL8857935 0.97 CHRM2 (0.32) CHRM2CHRM5CHRM3CHRM4KDM4E
Propylene Oxide SCHEMBL16267581 0.95 CHRM2 (0.31) CHRM2CHRM5CHRM3CHRM4KDM4E
Propylene Oxide SCHEMBL9873297 0.91 CHRM2 (0.37) CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL7556563 0.91 CHRM2 (0.37) CHRM2CHRM5CHRM3CHRM4
Propylene Oxide SCHEMBL168597 0.91
Propylene Oxide SCHEMBL9874479 0.91 CHRM2 (0.37) CHRM2CHRM5CHRM3CHRM4
Tetrahydrofuran SCHEMBL7167854 0.90 ALDH1A1 (0.38) KDM4EALDH1A1
Propylene Oxide SCHEMBL8374925 0.88 ALDH1A1 (0.35) CHRM2CHRM5CHRM3CHRM4ALDH1A1
Propylene Oxide SCHEMBL8761264 0.87 ALDH1A1 (0.40) CHRM2CHRM5CHRM3CHRM4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110520457-A Low density polyurethane elastomer foam with high ball rebound DOW GLOBAL TECHNOLOGIES LLC 2019-11-29 CN claimed
EP-1117715-A1 PROCESS FOR PREPARING HYDROPHOBICALLY MODIFIED LOW FOAMING COPOLYMERS, HYDROPHOBICALLY MODIFIED LOW FOAMING COPOLYMERS AND THEIR USE AS CEMENT ADDITIVES THE DOW CHEMICAL COMPANY (US) 2001-07-25 EP claimed
WO-2000014133-A1 PROCESS FOR PREPARING HYDROPHOBICALLY MODIFIED LOW FOAMING COPOLYMERS, HYDROPHOBICALLY MODIFIED LOW FOAMING COPOLYMERS AND THEIR USE AS CEMENT ADDITIVES THE DOW CHEMICAL COMPANY (US) 2000-03-16 WO claimed
EP-0985691-A1 Process for preparing hydrophobically modified low foaming copolymers, hydrophobically modified low foaming copolymers and their use as cement additives Dow Deutschland Inc., Zweigniederlassung Stade (DE) 2000-03-15 EP claimed
US-4439558-A Aqueous peroxide emulsion for use with glass fibers PPG INDUSTRIES, INC. (US) 1984-03-27 US claimed
US-4435473-A POLYMER REINFORCEMENT PPG INDUSTRIES, INC. (US) 1984-03-06 US claimed
US-4391876-A WITH NONIONIC EMULSIFIER PPG INDUSTRIES, INC. (US) 1983-07-05 US claimed
US-4334033-A CONTAINING NAPHTHALENE-1,5-DIISOCYANATE GROUPS BASF AKTIENGESELLSCHAFT (DE) 1982-06-08 US claimed
JP-7258600-A None JP disclosed
CN-114667320-B Curable composition and application method thereof 陶氏环球技术有限责任公司 2024-05-24 CN disclosed
CN-114641537-B Curable composition and method for bonding substrates 陶氏环球技术有限责任公司 2024-05-24 CN disclosed
CN-117413000-A Polyurethane product and method for producing a polyurethane product 陶氏环球技术有限责任公司 2024-01-16 CN disclosed
CN-116285641-A High-performance single-component polyurethane waterproof coating and preparation method thereof 北京东方雨虹防水技术股份有限公司 2023-06-23 CN disclosed
WO-2023000288-A1 POLYURETHANE COMPOSITIONS, PRODUCTS PREPARED WITH SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2023-01-26 WO disclosed
US-4469635-A EMULSIFIERS THE PROCTER & GAMBLE COMPANY (US) 1984-09-04 US disclosed
US-4363763-A DETERGENT SURFACTANTS THE PROCTER & GAMBLE COMPANY (US) 1982-12-14 US disclosed
US-4341677-A Antioxidants and reinforced polymers and oil-in-water emulsions of antioxidants PPG INDUSTRIES, INC. (US) 1982-07-27 US disclosed
EP-0034858-A2 Polyol esters of alpha-hydroxy carboxylic acids and compositions containing them THE PROCTER & GAMBLE COMPANY (US) 1981-09-02 EP disclosed
US-4125382-A Fuels containing polyoxyalkylene ether demulsifiers BASF WYANDOTTE CORPORATION (US) 1978-11-14 US disclosed
US-4029879-A Process for the removal of catalysts from polyether polyols employing water and adsorbent BASF WYANDOTTE CORPORATION (US) 1977-06-14 US disclosed