Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GNPAT | O15228 | 2/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL546909 | 0.88 | GSR (0.42) | SIRT6SIRT1FOLH1CPB2PAOX | |
| SCHEMBL13595628 | 0.82 | FOLH1 (0.54) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT | |
| SCHEMBL21673279 | 0.82 | FOLH1 (0.54) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT | |
| SCHEMBL20530 | 0.81 | FOLH1 (0.62) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT | |
| SCHEMBL20529 | 0.81 | FOLH1 (0.62) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT | |
| SCHEMBL919220 | 0.81 | FOLH1 (0.62) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT | |
| SCHEMBL97745 | 0.81 | CPB2 (0.41) | FOLH1CPB2 | |
| SCHEMBL16238796 | 0.79 | FOLH1 (0.60) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT | |
| Hydrochloric Acid SCHEMBL15669796 | 0.79 | FOLH1 (0.60) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT | |
| SCHEMBL31621381 | 0.79 | FOLH1 (0.60) | SIRT6SIRT1FOLH1SMN1; SMN2GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020187522-A1 | DNA encoding human Cid1 | ABBOTT LABORATORIES | 2002-12-12 | — | — | US | disclosed |
| US-20020127556-A1 | DNA encoding human Cid2 | ABBOTT LABORATORIES | 2002-09-12 | — | — | US | disclosed |
| WO-2002070554-A2 | DNA ENCODING HUMAN CID2 | ABBOTT LABORATORIES (US) | 2002-09-12 | — | — | WO | disclosed |